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AACR 2018: MET gene copy number gains evaluated by NGS is more predictive than other methods to enrich for papillary RCC patients sensitive to savolitinib

4541 / 26 - MET gene copy number gains evaluated by NGS is more predictive than other methods to enrich for papillary RCC patients sensitive to savolitinib, a selective MET inhibitor Presenter/Authors M. M. Frigault1, S. Signoretti2, A. Markovets

公告及新聞稿, 監管通知 | 2018-03-29

Total Voting Rights

London: Thursday, March 29, 2018: For information purposes, Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) hereby notifies the market that as at March 29, 2018, the issued share capital of Chi-Med consisted of 66,476,279 ordinary

公告及新聞稿, 監管通知 | 2018-03-28

Vesting of awards under the Long Term Incentive Plan

London: Wednesday, March 28, 2018: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) announces that following the publication of the 2017 annual report of Chi-Med on March 26, 2018, the following awards granted under the Long Term In

公告及新聞稿, 集團 | 2018-03-26

2017 Annual Report and Notice of Annual General Meeting

London: Monday, March 26, 2018: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) today announces that its 2017 Annual Report together with the Notice of Annual General Meeting and the Form of Proxy have been posted to shareholders.�

演示文稿, 科學出版物 | 2018-03-23

ASCPT 2018: Fruquintinib Pharmacokinetics in Humans

Pharmacokinetics of Fruquintinib in Humans Venue: American Society for Clinical Pharmacology & Therapeutics Annual Meeting in Orlando, Florida, USA Abstract #: PII-116 Authors: Ke Li, Chen Yu, Yanmei Liu, Xiangkun Li, Sumei Xia, Jian Wa

公告及新聞稿, 監管通知 | 2018-03-21

Director’s Share Dealing

London: Wednesday, March 21, 2018: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) has received notification that the spouse of Mr Graeme Jack, Independent Non-executive Director, purchased a total of 3,000 American Depositary Shar

公告及新聞稿, 監管通知 | 2018-03-20

Grant of Share Options under Share Option Scheme

London: Tuesday, March 20, 2018: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) announces that on March 19, 2018, it granted share options under the Share Option Scheme adopted by Chi-Med at its Annual General Meeting on April 24,

公告及新聞稿, 監管通知 | 2018-03-19

Director's Share Dealing

London: Monday, March 19, 2018: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) has received notification that Dr Dan Eldar, Non-executive Director, purchased a total of 2,768 American Depositary Shares of the Company (“ADSs”,

公告及新聞稿, 集團 | 2018-03-12

Publication of Form 20-F for the Year Ended December 31, 2017

公告及新聞稿, 集團 | 2018-03-12

Chi-Med Reports Final Results for the Year Ended December 31, 2017 and Updates Shareholders on Key Clinical Programs

Hutchison China MediTech Limited (“Chi-Med”) Reports Final Results for the Year Ended December 31, 2017 and Updates Shareholders on Key Clinical Programs Group: Year of major progress; results in line with guidance Group revenue up 12% to $

演示文稿, 科學出版物 | 2018-03-12

Journal of Clinical Oncology: Phase II Trial of Fruquintinib in Patients with Advanced Nonsquamous NSCLC

Shun Lu, Jianhua Chang, Xiaoqing Liu, Jianhua Shi, You Lu, Wei Li, Jin-ji Yang, Jianying Zhou, Jie Wang, Tongtong An, Lei Yang, Zhe Liu, Xiangdong Zhou, Mo Chen, Ye Hua and Weiguo Su Abstract Purpose Patients with advanced non‒small-cell lung

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2018-03-06

和黄医药在中国启动依吡替尼以胶质母细胞瘤为适应症的Ib/II期概念验证临床试验

1 個附件

2018年3月6日: 和黃醫藥今日宣佈在中國啟動依吡替尼Ib/II期概念驗證臨床試驗，目標受試者為表皮生長因子受體（EGFR）基因擴增的膠質母細胞瘤患者。膠質母細胞瘤是腦腫瘤的一種主要類型�

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演示文稿, 科學出版物 | 2018-02-24

ACOS 2018: Adverse Events of Special Interest Profiles and Time Courses of Fruquintinib in the FRESCO Trial

Venue: The 13th International Conference of the Asian Clinical Oncology Society in Chiang Mai, Thailand Abstract #: ABS093 Authors: Jin Li, Shukui Qin, Yuxian Bai, Yanhong Deng, Lei Yang, Zhendong Chen, Haijun Zhong, Rui-hua Xu, Hongming Pan,

演示文稿, 科學出版物 | 2018-02-20

ICTO2018: Phase Ib of Savolitinib and Durvalumab in Renal Cell Carcinoma (CALYPSO)

A Phase Ib Study of Durvalumab (MEDI4736) in Combination with Savolitinib in Patients with Metastatic Renal Cell Carcinoma S Vari1, B Szabados1, A GomezdeLiano1, K Mousa2, L Rammazzo2, A Prendergast2, T Powles1 1 Barts Health NHS Trust, Barts Can

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2018-02-13

和黃醫藥完成呋喹替尼以非小細胞肺癌為適應症的III期臨床試驗的患者入組工作，共招募527名患者

1 個附件

2018 年2 月13 日：和黃醫藥今日宣布呋喹替尼（HMPL-013）以非小細胞肺癌為適應症的III 期臨床試驗“FALUCA” 順利完成患者入組工作。呋喹替尼是一種高選擇性強效口服血管內皮生長因子受

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公告及新聞稿, 監管通知 | 2018-02-05

Chi-Med to Announce 2017 Final Results

London: Monday, February 5, 2018: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) will be announcing its final results for the year ended December 31, 2017 on Monday, March 12, 2018 at 7:00 am Greenwich Mean Time (GMT). An analy

公告及新聞稿, 監管通知 | 2017-12-29

Total Voting Rights

London: Friday, December 29, 2017: For information purposes, Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) hereby notifies the market that as at December 29, 2017, the issued share capital of Chi-Med consisted of 66,447,037 ordin

公告及新聞稿, 監管通知 | 2017-12-29

Blocklisting Six Monthly Return

London: Friday, December 29, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) announces the following blocklisting six monthly return: 1. Name of applicant: Hutchison China MediTech Limited 2. Name of scheme: H

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2017-12-15

和黃醫藥在美國啟動呋喹替尼臨床試驗

1 個附件

2017年12 月15日：和黃醫藥今日宣佈在美國啟動呋喹替尼I期橋接臨床試驗。呋喹替尼是一種高選擇性強效口服血管內皮生長因子受體（VEGFR）1,2及3的抑製劑。呋喹替尼在中國以結直腸癌、肺�

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公告及新聞稿, 監管通知 | 2017-11-01

TR-1: Notification of major interest in shares

公告及新聞稿, 監管通知 | 2017-11-01

TR-1: Notification of major interest in shares

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2017-10-31

和黃醫藥啟動呋喹替尼以二線胃癌為適應症的III期臨床研究FRUTIGA

1 個附件

2017年10月31日：和黃醫藥今日宣佈在中國啟動呋喹替尼聯合紫杉醇（泰素® ）以晚期胃癌或胃食管結合部（GEJ）腺癌為適應症的關鍵性III期臨床研究，這項研究被命名為FRUTIGA 。呋喹替尼是�

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公告及新聞稿, 集團 | 2017-10-30

Chi-Med Announces the Closing of U.S. Public Offering of American Depositary Shares (ADSs) Raising Approximately US$301.3 Million on the Nasdaq Global Select Market

London: Monday, October 30, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) announced today the closing of its underwritten public offering of American Depositary Shares ("ADSs") on the Nasdaq Global Select Market, previously

公告及新聞稿, 集團 | 2017-10-27

Chi-Med Announces the Full Exercise of Underwriters' Over-allotment Option

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, IN OR INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION London: Friday, October 27, 2017: Hutchison China MediTech L

公告及新聞稿, 集團 | 2017-10-26

Chi-Med Announces Pricing of U.S. Public Offering of ADSs Raising US$262 Million on Nasdaq Global Select Market (RNS)

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, IN OR INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION London: Wednesday, October 25, 2017: Hutchison China MediTec

新聞稿, 集團 | 2017-10-26

Chi-Med Announces Pricing of U.S. Public Offering of ADSs Raising US$262 Million on Nasdaq Global Select Market

London: Wednesday, October 25, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) announced today the pricing of the underwritten public offering previously announced by Chi-Med on October 24, 2017. Chi-Med will issue and sell 9

公告及新聞稿, 集團 | 2017-10-25

Chi-Med Announces Proposed Offering of ADSs (RNS)

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, IN OR INTO OR FROM ANY JURISDICTION WHERE TO DO SO WOULD CONSTITUTE A VIOLATION OF THE RELEVANT LAWS OF SUCH JURISDICTION London: Tuesday, October 24, 2017: Hutchison China MediTech

新聞稿, 集團 | 2017-10-24

Chi-Med Announces Proposed Offering of ADSs

London: Tuesday, October 24, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) announced today that it intends to offer, subject to market and other conditions, US$262.0 million of American Depositary Shares (“ADSs”), each

公告及新聞稿, 監管通知 | 2017-10-19

TR-1: Notification of major interest in shares

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2017-10-17

和黃醫藥聯合阿斯利康開發的沃利替尼二線治療MET擴增的EGFR突變肺癌患者展現出良好的臨床抗腫瘤活性

1 個附件

– 沃利替尼聯合泰瑞莎® 或易瑞沙® 的臨床研究數據於世界肺癌大會公佈– –新公佈的數據有助於理解MET 擴增的EGFR突變NSCLC的疾病進展過程和探索潛在的新一代治療策略–

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演示文稿, 科學出版物 | 2017-10-17

WCLC 2017: Phase Ib/II savolitinib plus Iressa® in MET-driven NSCLC

OA 09.06 – A Phase Ib Trial of Savolitinib plus Gefitinib for Chinese Patients with EGFR-Mutant MET-Amplified Advanced NSCLC Jin-Ji Yang, Jian Fang, Y. Shu, J. Chang, G. Chen, J. He, W. Li, X. Liu, N. Yang, Caicun Zhou, J. Huang, L. Yang, A.A. Han

演示文稿, 科學出版物 | 2017-10-17

WCLC 2017: Phase Ib/II savolitinib plus Tagrisso® in MET-driven NSCLC

OA 09.03 – TATTON Ph Ib Expansion Cohort: Osimertinib plus Savolitinib for Pts with EGFR-Mutant MET-Amplified NSCLC after Progression on Prior EGFR-TKI Myung-Ju Ahn, Ji-Youn Han, Lecia V Sequist, Byoung Chul Cho, J.S. Lee, Sang-We Kim, W. Su, C. T

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2017-10-16

和黃醫藥公佈呋喹替尼聯合療法用於肺癌一線治療的II期臨床研究初步結果

1 個附件

– 呋喹替尼聯合易瑞沙® （吉非替尼）展現出良好的療效和安全性– – 進一步證實呋喹替尼因其高選擇性和出眾的安全性而具有與其他癌症療法相聯合的巨大潛力– 2017年10

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演示文稿, 科學出版物 | 2017-10-15

WCLC 2017: Phase II fruquintinib combination with Iressa in NSCLC

JCSE 01.12 – A Phase II study of fruquintinib in combination with gefitinib in stage IIIb/IV NSCLC patients harboring EGFR activating mutations (NCT02976116) Shun Lu, Jianying Zhou, Xiaomin Niu, Mo Chen, Hongyan Yin, Ye Hua, Weiguo Su Venue: IA

公告及新聞稿, 新聞稿, 集團 | 2017-10-12

和黃醫藥董事會董事任命

1 個附件

2017 年10 月12 日：和黃中國醫藥科技有限公司（簡稱“ 和黃醫藥 ”或“Chi-Med”）（納斯達克/倫敦證交所：HCM）今日宣布任命莫樹錦（Tony Mok ）教授擔任公司獨立非執行董事，同時擔任

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公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2017-09-29

Chi-Med Highlights Oral Presentations at CSCO Annual Meeting

Press Release – Three oral presentations given at CSCO for fruquintinib, savolitinib and theliatinib – – Plenary keynote presentation for FRESCO Phase III trial details analysis showing consistent survival benefit in all key subgroups

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2017-09-29

Chi-Med to Present Savolitinib and Fruquintinib Clinical Data at WCLC 2017 Annual Meeting

Press Release – Data to show potential of savolitinib to treat EGFR-TKI resistance in both Iressa® and Tagrisso® refractory patients with MET amplification – – Results to further validate Chi-Med’s scientific strategy of designing highly

公告及新聞稿, 監管通知 | 2017-09-29

Total Voting Rights

London: Friday, September 29, 2017: For information purposes, Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) hereby notifies the market that as at September 29, 2017, the issued share capital of Chi-Med consisted of 60,750,132 ord

演示文稿, 科學出版物 | 2017-09-28

CSCO 2017: Savolitinib Phase Ib in c-MET Gastric Cancer

Phase Ib Trial of the Safety and Antitumor Activity of Savolitinib in Advanced Gastric Cancer Patients with Aberrant c-MET Jifeng Feng, Baorui Liu, Tianshu Liu, Nong Xu, Jianming Xu, Yunpeng Liu, Yuxian Bai, Jin Li, Wei Li, Chunmei Bai, Tao Zhang,

演示文稿, 科學出版物 | 2017-09-28

CSCO 2017: Theliatinib Phase I Results

Novel EGFR TKI Theliatinib: An Open Label, Dose Escalation Phase I Clinical Trial Lin Shen, Li Zhang, Hongyun Zhao, Wenfeng Fang, Jifang Gong Venue: Chinese Society of Clinical Oncology Annual Meeting Session: Esophageal Cancer Presenter: Jif

演示文稿, 科學出版物 | 2017-09-27

CSCO 2017: FRESCO In-Depth Analysis

In-depth Analysis of the FRESCO Study: a Randomized, Double-blind, Phase III Trial Evaluating the Efficacy and Safety of Fruquintinib in Patients with 3+ Line Advanced Colorectal Cancer Shukui QIN*, Jin LI*, Yuxian BAI, Yanhong DENG, Lei YANG, Zhen

演示文稿, 科學出版物 | 2017-09-27

CSCO 2017: Theliatinib Preclinical Study in Esophageal Cancer

Is EGFR a “feasible” target for advanced esophageal cancer treatment? Rongxin Ren, Shiming Fan, Linfang Wang,Min Cheng, Dongxia Shi, Wei Zhang,Renxiang Tang, Ying Yu, Longxian Jiao, Jun Ni, Haibin Yang, Huaqing Cai,Feng Zhou, Weihan Zhang, Wei

公告及新聞稿, 監管通知 | 2017-08-31

Director's Share Dealing

London: Thursday, August 31, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) has received notifications that Mr Simon To, Executive Director and Chairman, through Dynamic Drive Limited, a person closely associated with Mr To,

公告及新聞稿, 新聞稿, 腫瘤學 / 免疫學 | 2017-08-29

和黃醫藥在中國啟動高選擇性PI3Kδ抑製劑HMPL-689以淋巴瘤為適應症的I期臨床試驗

1 個附件

2017年8月29日：和黃醫藥今日宣佈在中國啟動HMPL-689的I期臨床試驗。HMPL-689是一種新型高選擇性強效小分子抑製劑，靶向B 細胞受體信號通路中的關鍵蛋白磷酸肌醇-3激酶δ異構體（PI3Kδ）。 �

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公告及新聞稿, 監管通知 | 2017-08-22

Director's Share Dealing

London: Tuesday, August 22, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) has received notifications that Ms Edith Shih, Non-executive Director and Company Secretary, purchased a total of 4,000 American Depositary Shares of

公告及新聞稿, 監管通知 | 2017-08-18

Directors' Share Dealing

London: Friday, August 18, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) has received notifications that:- (a) Mr Simon To, Executive Director and Chairman, through Wencheng Capital Limited (“WCL”), a person closely

公告及新聞稿, 監管通知 | 2017-08-15

Directors' Share Dealing

London: Tuesday, August 15, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) has received notifications that:- (a) Mr Simon To, Executive Director and Chairman, through Dynamic Drive Limited, a person closely associated (�

公告及新聞稿, 監管通知 | 2017-08-10

Director’s Share Dealing

London: Thursday, August 10, 2017: Hutchison China MediTech Limited ("Chi-Med") (AIM/Nasdaq: HCM) has received notifications that Ms Edith Shih, Non-executive Director and Company Secretary, purchased a total of 1,807 American Depositary Shares of th

公告及新聞稿, 監管通知 | 2017-08-07

Directors' Share Dealing

London: Monday, August 7, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM) has received notifications that:- (a) Mr Simon To, Executive Director and Chairman, through Dynamic Drive Limited, a person closely associated (“P

公告及新聞稿, 集團 | 2017-07-31

Chi-Med Reports 2017 Interim Results and Updates Shareholders on Key Clinical Programs

London: Monday, July 31, 2017: Hutchison China MediTech Limited (“Chi-Med”) (AIM/Nasdaq: HCM), the China-based biopharmaceutical company focused on discovering and developing targeted therapies for oncology and immunological diseases for the glob

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