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Major Shareholders

HUTCHMED has issued a total of 872,335,120 ordinary shares. Each Nasdaq-listed American Depositary Share (ADS) equates to five ordinary shares.

For illustrative purposes only, if converted in their entirety, this would be equivalent to 174,467,024 Nasdaq-traded ADSs.

Insofar as HUTCHMED is aware, approximately 40.05% of the issued share capital of HUTCHMED is not in public hands. Such percentage comprises the shares held by Directors, Executive Officers, and CK Hutchison Holdings Limited, a significant shareholder of HUTCHMED.

The disclosure of certain major and significant shareholdings in the share capital of HUTCHMED is governed by (i) the provisions of rule 5 of the Disclosure Guidance and Transparency Rules of the U.K. Financial Conduct Authority (DTR) (which have been incorporated by reference into the Company's Articles of Association); (ii) the US Securities Exchange Act of 1934; and (iii) the Hong Kong Securities and Futures Ordinance (Cap. 571) ("SFO").

Insofar as HUTCHMED is aware, the interests of its shareholders holding 3% or more of the issued share capital of HUTCHMED and its directors are set out in the tables below.

Last updated: April 14, 2026

Significant Shareholders

Name Total Number of Shares Held / Interested Approx. % of Total Issued Shares
CK Hutchison Holdings Limited ("CKHH") 332,632,780 38.13%
CA Fern Parent 30,847,500 3.54%
M&G Plc 27,618,355 3.17%
Notes:
The above table sets out the interests of certain shareholders who have disclosed their interests pursuant to Part XV of the SFO or other applicable notification requirements under applicable stock exchanges, or whose interests are otherwise known to HUTCHMED.

Directors

Name Total Number of Shares/Underlying Shares Held Approx. % of Total Issued Shares
Weiguo SU 12,333,776 1.41%
Johnny CHENG 2,936,430 0.34%
Edith SHIH 1,200,000 0.14%
Dan ELDAR 150,660 0.02%
Renu BHATIA 16,000 0.002%
Total 16,636,866 1.91%
Notes: As of December 31, 2025. Includes the interests and short positions of the Directors and chief executive of the Company in the shares, underlying shares and debentures of the Company or any of its associated corporations (within the meaning of Part XV of the Securities and Futures Ordinance (Chapter 571 of the Laws of Hong Kong) (the “SFO”)) which were notified to the Company and The Stock Exchange of Hong Kong Limited (the “HKEX”) pursuant to Divisions 7 and 8 of Part XV of the SFO (including interests and short positions which the Directors and chief executive of the Company were deemed or taken to have under such provisions of the SFO), or which were recorded in the register required to be kept by the Company pursuant to Section 352 of the SFO, or as otherwise notified to the Company and the HKEX pursuant to the Code on Dealings in Shares by Directors adopted by the Company. For details of the capacity and nature of each Director’s interests, please refer to the “Directors’ and Chief Executives’ Interests and Short Positions in Shares, Underlying Shares and Debentures” section in the 2025 Annual Report.