The Stock Exchange of Hong Kong Limited, also known as HKEX, is the Hong Kong stock exchange. Additional information is available at www.hkexnews.hk.

The Nasdaq Stock Market, also known as simply Nasdaq, is an American stock exchange. It is the second-largest stock exchange by market capitalization in the world, after the New York Stock Exchange. Additional information is available at www.nasdaq.com.

AIM is the London Stock Exchange's international market for growth companies and it is the most successful growth market in the world. Additional information is available at www.londonstockexchange.com.

HUTCHMED’s ordinary shares are traded on the HKEX in the form of ordinary shares.

HUTCHMED’s ordinary shares are traded on AIM and trades are settled electronically through the CREST system in the form of depositary interests (“DIs”). HUTCHMED’s ordinary shares traded on AIM are held by a depositary, Computershare Investor Services PLC (“Computershare”). Computershare issues DIs representing the underlying ordinary shares on a one-for-one basis and maintains a register of DI holders. The corresponding ordinary shares are held by Computershare on trust for the holders of DIs.

CREST is a paperless settlement procedure enabling securities to be evidenced other than by a certificate and transferred other than by a written instrument, so that trades can settle electronically. Securities issued by non-U.K. companies, such as the ordinary shares of HUTCHMED, cannot be directly held or transferred under the CREST system, which is why DIs are required.

A DI is a facility created to enable HUTCHMED’s ordinary shares to be delivered, held and settled under the CREST system. Each DI will be treated as one ordinary share for the purposes of determining, for example, entitlement to dividends, voting rights, participation in pre-emptive follow-on offerings and returns of capital. DIs are a common feature of the AIM market and are used by many non-U.K. AIM companies.

HUTCHMED’s ordinary shares are traded on Nasdaq in the form of American depositary shares (“ADSs”). As a result, a portion of HUTCHMED’s ordinary shares are held by its ADS depositary bank, Deutsche Bank Trust Company Americas (“Deutsche Bank”), which ordinary shares underly the ADSs held by U.S. shareholders. The ADSs are a common feature used by non-U.S. companies on the Nasdaq Stock Market.

An ADS represents ownership of shares in a non-U.S. corporation. ADSs are quoted and traded in U.S. dollars in the U.S. securities markets. ADS dividends are paid to investors in U.S. dollars. ADSs were specifically designed to facilitate the purchase, holding and sale of non-U.S. securities by U.S. investors.

This ratio reflects the number of ordinary shares that correspond to one ADS. In the case of HUTCHMED, each ADR represents five ordinary shares.

A depositary is an entity which facilitates cross-border trading of an issuer’s shares. Among other things, depositaries provide ADS and DI issuance and cancellation services, and associated share transfer services such as maintaining the register of ADS or DI holders, distributing dividends to ADS and DI holders, providing annual meeting services and executing corporate actions. So, in practice, Deutsche Bank and Computershare, as the depositaries, maintain records of the holders of ADSs and DIs, respectively, and manage the flow of shares between the two separate markets, essentially converting DIs into ADSs when there is demand in the U.S., and converting ADSs back into DIs when there is demand for the DIs in the U.K. This service facilitates liquidity between the two markets with the objective that any price differential between the two markets is kept to a minimum.

You can buy ordinary shares, ADSs or DIs through a broker, just as you would any other Hong Kong, U.S. or U.K. security. When you instruct your broker to buy HUTCHMED’s ordinary shares on your behalf, your broker will have the option of buying ordinary shares on HKEX, ADSs on Nasdaq or DIs on AIM. Conversely, when you wish to sell your position, your broker will either sell them on HKEX, Nasdaq or AIM. Any necessary conversion of securities would first be effected in the manner described below. In any event, this would be a seamless process for shareholders. Unless shareholders particularly wish to give specific instructions in that regard (in which case they are free to do so), they will not need to be concerned with which market their shares are purchased from or sold into. Brokers will simply buy or sell in the market where there is the most liquidity at that time.

Yes, it is permissible for holders of ordinary shares, ADSs or DIs to purchase HUTCHMED’s other securities (for example, an ADS holder may purchase DIs and/or ordinary shares through its broker) or to convert some or all of their HUTCHMED securities from ordinary shares, DIs or ADSs into one of its other listed securities.  The conversion process is described in further detail below. We would advise that shareholders seek advice from their broker and/or tax adviser.

A more detailed explanation of the steps for conversion can be found here. To enquire regarding transferring shares to be traded on AIM or HKEX, please contact the Registrar, Computershare. To enquire regarding conversion of shares into Nasdaq-traded ADSs, please contact the ADS Depositary, Deutsche Bank. Contact information is available below.

ADS Depositary Contact Information – Deutsche Bank Trust Company Americas

DR Markets Distribution

CREST Depositary Contact Information – Computershare Investor Services PLC

The Pavilions
Bridgwater Road
Bristol BS99 6ZY
United Kingdom

Hong Kong Share Registrar contact information:

Computershare Hong Kong Investor Services Limited

Rooms 1712-1716, 17th Floor Hopewell Centre
183 Queen’s Road East
Wanchai, Hong Kong

 
Principal Share Registrar contact information:

Computershare Investor Services (Jersey) Limited

13 Castle Street
St. Helier
Jersey, JE1 1ES
Channel Islands
Tel: +44 (0)370 707 4040
 

Holders of ADSs/DIs may authorize HUTCHMED’s applicable depositary, Deutsche Bank or Computershare, to act as a proxy in exercising voting rights in accordance with the ADS/DI holder's directions according to the number of ordinary shares represented by their respective ADSs/DIs.

You can send an email to investor relations requesting to be notified of any new updates announced here.

HUTCHMED’s annual report, interim report and other press releases can be downloaded from HUTCHMED’s website.

PriceWaterhouseCoopers.