HUTCHMED - Major Shareholders

HUTCHMED has issued a total of 872,148,995 ordinary shares. Each Nasdaq-listed American Depositary Share (ADS) equates to five ordinary shares.

For illustrative purposes only, if converted in their entirety, this would be equivalent to 174,429,799 Nasdaq-traded ADSs.

Insofar as HUTCHMED is aware, approximately 40.06% of the issued share capital of HUTCHMED is not in public hands. Such percentage comprises the shares held by Directors, Executive Officers, and CK Hutchison Holdings Limited, a significant shareholder of HUTCHMED.

The disclosure of certain major and significant shareholdings in the share capital of HUTCHMED is governed by (i) the provisions of rule 5 of the Disclosure Guidance and Transparency Rules of the U.K. Financial Conduct Authority (DTR) (which have been incorporated by reference into the Company's Articles of Association); (ii) the US Securities Exchange Act of 1934; and (iii) the Hong Kong Securities and Futures Ordinance (Cap. 571) ("SFO").

Insofar as HUTCHMED is aware, the interests of its shareholders holding 3% or more of the issued share capital of HUTCHMED and its directors are set out in the tables below.

Last updated: September 5, 2025

Name	Total Number of Shares Held / Interested	Approx. % of Total Issued Shares
CK Hutchison Holdings Limited ("CKHH") ⁽¹⁾	332,574,650	38.13%
M&G Plc ⁽²⁾	43,173,457	4.95%
CA Fern Parent ⁽³⁾	30,847,500	3.54%

Notes:

The above table sets out the interests of certain shareholders, insofar as HUTCHMED is aware based on public disclosure as of June 30, 2025. Includes the interests and short positions in the shares or underlying shares of the Company which would fall to be disclosed to the Company under the provisions of Divisions 2 and 3 of Part XV of the SFO, or which were recorded in the register required to be kept by the Company under Section 336 of the SFO, or as otherwise notified to the Company and HKEX under Part XV of the SFO. For details of the capacity of each substantial shareholder’s interests, please refer to the “Interests and Short Positions of Shareholders Discloseable under the Securities and Futures Ordinance” section in the 2025 Interim Report. The above table includes Long Positions only – excludes short positions and lending pools.

This table excludes interests of Deutsche Bank Aktiengesellschaft, which include the interests of Deutsche Bank Trust Company Americas acting in its capacity as a depositary of the American depositary receipts program of the Company.

(1) Please refer to 2025 Interim Report for details. As of July 15, 2021, notified via disclosure form 2 filed with the Hong Kong Stock Exchange on July 19, 2021. (2) As of November 2, 2023, notified via disclosure form 2 filed with the Hong Kong Stock Exchange on November 3, 2023. An aggregated 43,173,457 ordinary shares (long position) are held by M&G Plc indirectly through its certain subsidiaries. (3) CA Fern Parent is wholly owned by several entities which are, by and through their control affiliates (including their respective general partners), ultimately controlled (directly or indirectly) by The Carlyle Group Inc., but The Carlyle Group Inc. has no beneficial interest in the underlying securities of the Company. As of August 20, 2024, notified via disclosure form TR-1 filed on AIM on August 22, 2024.

Name	Total Number of Shares/Underlying Shares Held	Approx. % of Total Issued Shares
Weiguo SU	12,333,776	1.41%
Johnny CHENG	2,936,430	0.34%
Edith SHIH	1,200,000	0.14%
Dan ELDAR	150,660	0.02%
Tony MOK	136,705	0.02%
Renu BHATIA	16,000	0.002%
Total	16,773,571	1.92%

Notes: As of June 30, 2025. Includes the interests and short positions of the Directors and chief executive of the Company in the shares, underlying shares and debentures of the Company or any of its associated corporations (within the meaning of Part XV of the Securities and Futures Ordinance (Chapter 571 of the Laws of Hong Kong) (the “SFO”)) which were notified to the Company and The Stock Exchange of Hong Kong Limited (the “HKEX”) pursuant to Divisions 7 and 8 of Part XV of the SFO (including interests and short positions which the Directors and chief executive of the Company were deemed or taken to have under such provisions of the SFO), or which were recorded in the register required to be kept by the Company pursuant to Section 352 of the SFO, or as otherwise notified to the Company and the HKEX pursuant to the Code on Dealings in Shares by Directors adopted by the Company. For details of the capacity and nature of each Director’s interests, please refer to the “Directors’ and Chief Executives’ Interests and Short Positions in Shares, Underlying Shares and Debentures” section in the 2025 Interim Report.

Significant Shareholders

Directors