Holding(s) in Company

For filings with the FCA include the annex

For filings with issuer exclude the annex

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESⁱ

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are
attached: ⁱⁱ

Hutchison China
MediTech Limited

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

Change in total voting rights of the issuer

ü

3. Full name of person(s) subject to the notification obligation: ⁱⁱⁱ

Hutchison Healthcare Holdings Limited

4. Full name of shareholder(s)
 (if different from 3.):^iv

5. Date of the transaction and date on which the threshold is crossed or reached: ^v

22 March 2016

6. Date on which issuer notified:

22 March 2016

7. Threshold(s) that is/are crossed or reached: ^{vi, vii}

64%

8. Notified details:

A: Voting rights attached to shares ^{viii, ix}

Class/type of
shares

if possible using the ISIN CODE

Situation previous
to the triggering
transaction

Resulting situation after the triggering transaction

Number
of Shares

Number
of Voting
Rights

Number
of shares

Number of voting
rights

% of  voting rights ^x

Direct

Direct ^xi

Indirect ^xii

Direct

Indirect

Ordinary

36,666,667

36,666,667

36,666,667

36,666,667

60.82

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial
instrument

Expiration date ^xiii

Exercise/Conversion Period ^xiv

Number of voting
rights that may be
acquired if the
instrument is
exercised/ converted.

% of voting
rights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments ^{xv, xvi}

Resulting situation after the triggering transaction

Type of financial
instrument

Exercise price

Expiration date ^xvii

Exercise/
Conversion period ^xviii

Number of voting
rights instrument refers to

% of voting
rights ^xix,
xx

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

36,666,667

60.82%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: ^xxi

Hutchison Healthcare Holdings Limited is a wholly owned subsidiary of Hutchison Whampoa (China) Limited, which is an indirect wholly-owned subsidiary of CK Hutchison Holdings Limited – 36,666,667 ordinary shares (60.82%)

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will
cease to hold:

12. Date on which proxy holder will cease to
hold voting rights:

13. Additional information:

14. Contact name:

Edith Shih

15. Contact telephone number:

+852 2128 1232